R Grace Zhai Selected Research

Nicotinamide-Nucleotide Adenylyltransferase

12/2021	NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis.
10/2019	Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence.
9/2019	MicroRNA miR-1002 Enhances NMNAT-Mediated Stress Response by Modulating Alternative Splicing.
1/2013	The role of autophagy in Nmnat-mediated protection against hypoxia-induced dendrite degeneration.
5/2011	Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway.
11/2006	Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity.

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R Grace Zhai Research Topics

Disease

5	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2019 - 04/2008
4	Snyder Robinson syndrome 01/2022 - 11/2017
3	Neoplasms (Cancer) 01/2022 - 09/2011
2	Hypoxia (Hypoxemia) 01/2013 - 05/2011
2	Frontotemporal Dementia (Semantic Dementia) 01/2012 - 01/2012
2	Tauopathies 01/2012 - 01/2012
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2022
1	Glioma (Gliomas) 12/2021
1	Rare Diseases (Rare Disease) 11/2021
1	Diabetic Neuropathies (Diabetic Neuropathy) 01/2020
1	type 1 Pena Shokeir syndrome 10/2019
1	Sensorineural Hearing Loss 01/2019
1	Peripheral Nervous System Diseases (PNS Diseases) 12/2018
1	Nervous System Diseases (Neurological Disorders) 11/2017
1	Intellectual Disability (Idiocy) 11/2017
1	Undiagnosed Diseases 01/2017
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 11/2015
1	Alzheimer Disease (Alzheimer's Disease) 01/2012
1	Warts (Wart) 09/2011
1	Parkinsonian Disorders (Parkinsonism) 11/2010
1	Dementia (Dementias) 11/2010
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2010
1	Wallerian Degeneration 11/2006

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 12/2021 - 11/2006
6	Nicotinamide-Nucleotide AdenylyltransferaseIBA 12/2021 - 11/2006
4	Spermine SynthaseIBA 01/2022 - 11/2017
4	EnzymesIBA 12/2021 - 11/2017
4	NAD+ synthaseIBA 12/2021 - 11/2006
2	PolyaminesIBA 01/2022 - 11/2017
2	NAD (NADH)IBA 12/2021 - 01/2012
2	Amino Acids FDA Link 01/2018 - 11/2010
2	Nicotinamide MononucleotideIBA 04/2013 - 01/2012
2	Phosphotransferases (Kinase)IBA 01/2013 - 09/2011
1	AcetylesteraseIBA 01/2022
1	SpermineIBA 11/2021
1	ProdrugsIBA 11/2021
1	polyolIBA 01/2020
1	Sorbitol (Yal)FDA Link 01/2020
1	FructoseIBA 01/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 12/2018
1	Uridine Diphosphate (UDP)IBA 01/2017
1	Protein Isoforms (Isoforms)IBA 11/2015
1	Messenger RNA (mRNA)IBA 11/2015
1	glutamine-synthetase adenylyltransferaseIBA 01/2012
1	tau Proteins (tau Protein)IBA 01/2012
1	Alanine (L-Alanine)FDA Link 11/2010
1	Molecular Chaperones (Chaperone, Molecular)IBA 10/2010

Therapy/Procedure

1	Therapeutics 12/2021
1	Drug Therapy (Chemotherapy) 12/2018